Method Development
Development of LC-MS/MS assays for clinical, toxicology, hormone, amino acid, vitamin, and specialty testing applications.
Expert Services
Expert LC-MS/MS Support
When the problem needs deeper investigation, expert LC-MS/MS consulting is available.
When the Run Review Points to a Real Problem
When the Run Review Points to a Real Problem
LC/MS-IQ helps identify calibration, QC, signal, retention time, and analyte performance issues. When the problem needs deeper investigation, expert LC-MS/MS consulting is available.
Common Ways We Help
Common Ways We Help
Review a failed or unstable LC-MS/MS method
Help prepare a validation plan before data collection begins
Review calibration and QC trends from LC/MS-IQ
Assist with method transfer or troubleshooting between instruments
Improve sample preparation, chromatography, or integration rules
Support CAP/CLIA documentation and technical review
Method Validation
CLIA and CAP validation support including precision, accuracy, linearity, carryover, LOD, LOQ, and comparison studies.
Troubleshooting
Retention time shifts, low signal, ion suppression, carryover, calibration failures, QC issues, and assay instability.
Laboratory Automation
Workflow optimization, liquid handling automation, high-throughput processing, and laboratory efficiency improvements.
LDT Development
Support for laboratory developed tests from feasibility through validation and implementation.
Quality & Compliance
Assistance with documentation, SOPs, validation packages, CAP inspections, and quality programs.
Behind the Science
Behind the Science
LC/MS-IQ is built on extensive experience in LC-MS/MS laboratory operations, method development, validation, troubleshooting, automation, and quality systems.
Its design is informed by experience supporting hundreds of laboratories nationwide, managing high-volume clinical laboratory operations performing millions of tests annually, and working with LC-MS/MS laboratories across the United States.
Request Expert Assistance
Request Expert Assistance
Calibration failures, QC drift, low signal, validation planning, method development, automation projects, or difficult troubleshooting issues. Describe the problem and we'll review your request.
Need Help With an LC-MS/MS Problem?
Need Help With an LC-MS/MS Problem?
Whether you are developing a new assay, troubleshooting an existing method, preparing for validation, or improving laboratory operations, we're available to help.